It can, but if the subfloor is covered by carpet or padding, you may want to consider the OdorKlenz Subfloor Treatment Kit in addition to the OdorKlenz Pet Urine Eliminator. More on that product can be founds here: https://www.odorklenz.com/product/odorklenz-subfloor-treatment-kit/
anything with enzymes will work in a spray bottle also , i have same issue ! going to have to replace carpet and not sure what to put back down ! have you tried some pee pads ? just lay a couple down at night !
Wash urine collection devices thoroughly. Disinfect reusable parts with commercial cleansers or with a solution containing one part white vinegar and two parts water. Don’t bother with bleach, which is harsh and does not dissolve urine crystals as well as vinegar.
In your lifetime, your kidneys filter more than one million gallons of water, enough to fill a small lake. Amazingly, one kidney can handle the task perfectly well. In fact, if you lose a kidney, your remaining kidney can increase in size by 50 percent within two months, to take over the job of both.3
If you suffer from the dog/cat pee problem and don’t have the ability or money to install tile, then buy indoor/outdoor carpet. The new stuff at Lowes feels like real carpet without the problems of it.
Thank you Thank you Thank you. I spent my whole weekend cleaning my family room carpet with a carpet cleaning machine, about 3-4 times. Today it STILL smelled like urine. I tried the recipe and it worked GREAT. I put the vinegar/water mixture in my machine and went over the stinky area. My carpets are pretty dry after the machine sucks all the water up so I went right to the next step and a few hours later I am crawling around on my hands and knees trying to find the urine smell but it is nowhere to be found!!!! : )
Avoid ammonia. High in alkaline, ammonia should never be used to clean pet stains. It will leave a sticky residue in the carpet and damage the carpet fibers, attracting dirt and other debris. It will also attract pets back to the same area, because ammonia contains the same uric acids and salts that are present in urine, making it all too tempting for your pet to remark the area. Never use ammonia on pet stains. [3]
If you find that your pup is peeing a lot inside of the crate then there is very likely a medical problem. Some dogs – females especially – just have weak bladders, too. So that’s always a factor. That’s really hard to deal with, but sometimes medication from veterinarians can help.
Funnel 7 tablespoons of brown sugar into your container, and add the fruit. Next, add the water, and tightly screw on the cap, giving everything a good shake to mix it around. Loosen the cap and leave it on halfway to release the gases and ensure your bottle doesn’t explode due to the build-up. After 3 months, you’re natural enzymatic cleaner will be ready to use!
Urine usually has a distinct odor, but under normal circumstances, the odor is relatively mild and not too noticeable. Certain conditions, however, may cause your urine to have an unusual or unpleasant odor, which may raise concerns about a problem or abnormality.
Finally, if you do want to use a perfumed product to help neutralize the smell, make sure that it is non-toxic to animals. Many products that are safe for humans are not always safe for dogs. Some home air fresheners – sprays, plug-ins and scented oils – can be harmful to a pet’s health, so when in doubt, just stick with the tried and true baking soda solution.
Add a bit of bleach into the water (ratio of 1:10) and stir it. Apply the resulting mixture on the spot where your dog left some pee. In 20 minutes wash the whole surface or even the whole carpet with the water.
CR’s take: The Rug Doctor Mighty Pro X3 has front-to-back sliding brushes instead of rotational brushes, like other carpet cleaners, similar to the commercial version of the Rug Doctor you can rent. It’s relatively heavy at 43 pounds and takes 3 gallons of water to fill its tank—easily adding up to 25 pounds to its weight—and wasn’t very intuitive when our testers went to fill it up. It does have a long hose, at 155 inches, so you won’t have to lug it at every turn, and its dryness score is Excellent. But unless you have a lot of carpet to clean and plan to clean often, you might want to consider a lighter model. 
I am often contacted by readers of my articles. This is the story of one reader, Sophia. She told me about her experience with carpets that smelled of dog urine in a house that her family has recently moved into.
It takes three days to put one carpet cleaner through our battery of cleaning-performance tests. Our engineers soil large swatches of off-white nylon carpet with red Georgia clay. We run a cleaner over the carpet for four wet and four dry cycles, simulating how you’d clean a particularly dirty spot on a well-trafficked carpet. Then we repeat the test on two more swatches.
Be warned, you may want to not be as vocal as I was when I was so impressed with the results that this cleaner had produced. It cleaned so well that I told my ENTIRE extended family and now everyone wants to try (borrow) mine, grrrr…. I’m literally having to organize a schedule so I can get it back in time to clean our rugs as I want to clean them at least twice a month so they do not get as bad as they were EVER again! I told everyone that I want it to come back with a “FULL TANK” LOL *meaning I want a FULL container of cleaning solution when it finally gets back to me! 😉
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Please do not use bleach! You will strip the carpet fibers of the color dye. If you would like to learn how to remove pet odors and stains please call a professional Like Benchmark Restoration & Cleaning

For more stubborn stains and aromas, there are several green enzymatic cleaners you can find to spray on your carpet or, if you have older stains to tackle, consider renting a carpet-cleaning machine from a local store. Rinse the tank out well before use and don’t use the chemical-heavy cleanser that’s often sold with the rental. Instead, Bond recommends using a natural cleaner or a combination of white vinegar and water.
Let’s face it: Most of us don’t give much thought to our pee before we flush it out of sight. But the basic details of your urine — color, smell, and how often you go — can give you a hint about what’s going on inside your body.
Foamy: No matter what color it is, you should check in with your doctor if it consistently looks foamy and frothy. It may be a sign you have protein in your urine, which may mean you have issues with your kidneys.
No need to worry about staining either, this product breaks down the stains which can emerge from urine in a natural way. This allows things to get settled out and leave you with a clean floor that only has the cleaner’s scent to it.
I​’m interested in the intersection between design and technology​—whether for ​drywall or robotic vacuums—and how the resulting combination affects consumers. I’ve written about consumer advocacy issues for publications like The Atlantic, PC Magazine, and Popular Science, and now I’m happy to be tackling the topic for CR. For updates, feel free to follow me on Twitter (@haniyarae).